Source Localization accuracy in an animal model

Source localization in the human brain based on EEG and MEG data becomes more and more important in the field of clinical research and routine. Thus, information about source localization accuracy is indispensable. Source localization accuracy has been tested with various artificial source and volume conductor models. However, there are a number of limitations inherent to these artificial models. Thus, we address source localization accuracy with an animal model. Furthermore, most investigations have been performed with artificial and physiological sources of a tangential orientation. However, 20 percent of the sources of the human brain have a radial orientation. Hence, an animal model with a lissencephalic cerebrum (flat cortical surface) with radial oriented physiological sources would take this into account.